We study the molecular mechanisms underlying chemosensation and temperature sensation.
Lab News
- Jinhong Receives IIN Outstanding Researcher Leader Award
Congratulations to Jinhong Hu on receiving the 2026 Outstanding Researcher Leader Award from Northwestern University’s International Institute for Nanotechnology (IIN).
- Jiangnan Receives CLP CAURS Award
Congratulations again to Jiangnan Sheng on receiving a 2026–2027 CLP Chicago Area Undergraduate Research Symposium (CAURS) Award from Northwestern University’s Chemistry of Life Processes Institute (CLP) to support research in our lab.
- Jiangnan Awarded Undergraduate Research Grant
Congratulations to Jiangnan Sheng on receiving an Academic Year Undergraduate Research Grant from Northwestern University’s Office of Undergraduate Research to support research in our lab.
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Latest Papers
Dynamic dimer-of-dimers architecture defines Mg2+ transport in human CNNM4
Bai Z, Zhou E, Lü W#, Du J# (2026) Cell.
Temperature and intrinsic Ca2+ reshape TRPM4 pharmacology
Hu J, Ievleva S, Park SJ, Lee J, Cheng J, O’Dea G, Sheng J, Du J#, Lü W# (2026) Nature Structural & Molecular Biology.
Noncanonical calcium-independent TRPM4 activation governs intestinal fluid homeostasis
Liu Y$, Hu J$, Xue C$, Huang W$, Ievleva S, Lü W#, Du J#, Cao Z# (2026) Nature Communications.
A single allosteric site merges activation, modulation and inhibition in TRPM5
Ruan Z, Lee J, Li Y, Orozco I, Du J#, Lü W# (2026) Nature Chemical Biology.