We study the molecular mechanisms underlying chemosensation and temperature sensation.
Lab News
- Welcome summer interns Kellie Wu and Alex Liu
Kellie is a second-year undergraduate student pursuing a B.S. in Biochemistry at Case Western Reserve University.
Alex has just completed his first year at University of California, Berkeley and has returned to the lab for a summer internship. - Sarah Awarded NIH F31 Fellowship
Congratulations to Sarah Keuning on receiving an F31 fellowship from the National Institute of Neurological Disorders and Stroke for her research on CALHM channels!
- Garrett promoted to lab manager
Congratulations to Garrett on his promotion, effective May 1, 2026. We are grateful for his contributions to the lab!
More ››
Latest Papers
Temperature and intrinsic Ca2+ reshape TRPM4 pharmacology
Hu J, Ievleva S, Park SJ, Lee J, Cheng J, O’Dea G, Sheng J, Du J#, Lü W# (2026) bioRxiv.
Noncanonical calcium-independent TRPM4 activation governs intestinal fluid homeostasis
Liu Y$, Hu J$, Xue C$, Huang W$, Ievleva S, Lü W#, Du J#, Cao Z# (2026) Nature Communications.
A single allosteric site merges activation, modulation and inhibition in TRPM5
Ruan Z, Lee J, Li Y, Orozco I, Du J#, Lü W# (2026) Nature Chemical Biology.