We study the molecular mechanisms underlying chemosensation and temperature sensation.
Lab News
- Sophia Du and Sarah Wang Receive MBS Summer Fellowships
Sophia and Sarah, both undergraduates at Northwestern University, have been awarded summer fellowships from the Department of Molecular Biosciences. The fellowships will support eight weeks of full-time summer research in the lab. Congratulations!
- Welcome to our newest lab member, Chhandosee Ganguly!
She joined the lab today as a postdoctoral fellow.
- Our preprint on how temperature and calcium reshape TRPM4 pharmacology is now published in NSMB
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Latest Papers
Temperature and intrinsic Ca2+ reshape TRPM4 pharmacology
Hu J, Ievleva S, Park SJ, Lee J, Cheng J, O’Dea G, Sheng J, Du J#, Lü W# (2026) Nature Structural & Molecular Biology.
Noncanonical calcium-independent TRPM4 activation governs intestinal fluid homeostasis
Liu Y$, Hu J$, Xue C$, Huang W$, Ievleva S, Lü W#, Du J#, Cao Z# (2026) Nature Communications.
A single allosteric site merges activation, modulation and inhibition in TRPM5
Ruan Z, Lee J, Li Y, Orozco I, Du J#, Lü W# (2026) Nature Chemical Biology.