Lab News

• Garrett promoted to lab managerMay 5, 2026

  Congratulations to Garrett on his promotion, effective May 1, 2026. We are grateful for his contributions to the lab!

• Celebrating Sofia’s Ph.D. GraduationMay 4, 2026

  We are delighted to celebrate the successful Ph.D. graduation of Sofia Ievleva. Sofia has been a valued member of the lab, and it has been a true pleasure to watch her grow and develop as a scientist. We are grateful for her contributions and wish her all the best in her next chapter and continued success in her future endeavors.

  

• Welcome Felix Weng to the labMay 3, 2026

  Felix joined the lab as a postdoctoral fellow on May 1.

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Latest Papers

Temperature and intrinsic Ca²⁺ reshape TRPM4 pharmacology
Hu J, Ievleva S, Park SJ, Lee J, Cheng J, O’Dea G, Sheng J, Du J^#, Lü W^# (2026) bioRxiv.

Noncanonical calcium-independent TRPM4 activation governs intestinal fluid homeostasis
Liu Y^$, Hu J^$, Xue C^$, Huang W^$, Ievleva S, Lü W^#, Du J^#, Cao Z^# (2026) Nature Communications.

A single allosteric site merges activation, modulation and inhibition in TRPM5
Ruan Z, Lee J, Li Y, Orozco I, Du J^#, Lü W^# (2026) Nature Chemical Biology.

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