We study the molecular mechanisms underlying chemosensation and temperature sensation.

UN_campus

Lab News

  • Alex Liu returns to the lab

    Alex just finished his first year at the University of California, Berkeley and has returned to the lab for a summer internship. Welcome back, Alex!

  • Sarah Awarded NIH F31 Fellowship

    Congratulations to Sarah Keuning on receiving an F31 fellowship from the National Institute of Neurological Disorders and Stroke for her research on CALHM channels!

  • Garrett promoted to lab manager

    Congratulations to Garrett on his promotion, effective May 1, 2026. We are grateful for his contributions to the lab!

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Latest Papers

Temperature and intrinsic Ca2+ reshape TRPM4 pharmacology
Hu J, Ievleva S, Park SJ, Lee J, Cheng J, O’Dea G, Sheng J, Du J#, Lü W# (2026) bioRxiv.

Noncanonical calcium-independent TRPM4 activation governs intestinal fluid homeostasis
Liu Y$, Hu J$, Xue C$, Huang W$, Ievleva S, Lü W#, Du J#, Cao Z# (2026) Nature Communications.

A single allosteric site merges activation, modulation and inhibition in TRPM5
Ruan Z, Lee J, Li Y, Orozco I, Du J#, Lü W# (2026) Nature Chemical Biology.

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