Published today in Nature Communications: the laxative bisacodyl and its active metabolite directly activate TRPM4 to regulate intestinal fluid homeostasis. A great collaboration with Dr. Cao’s lab at China Pharmaceutical University!
New year, new publication
A unified allosteric site controls TRPM5 function, published today in Nature Chemical Biology.
Our paper on ATP permeation and mefloquine potentiation of PANX1 is published today
After 26 months (!) from initial submission to publication, our PANX1 study is finally out in Nature Communications! The extremely long review process made this a truly memorable experience (for better or worse), and the team’s persistence and dedication carried it through.
Thanks to everyone on the PANX1 team for their hard work and resilience!
Our reviewed preprint on understudied CALHM channels is published at eLife today
Through our collaboration with the Kannan lab at the University of Georgia, we reveal conserved gating determinants in understudied CALHM ion channels using an evolutionary analysis approach combined with electrophysiology.
Congratulations to Sarah on passing her Qualifying Exam
A major milestone — She is now officially a PhD candidate!
Two IBiS rotation students join
Welcome Anna Gilstrap and Tisha Dash!
Sarah Keuning officially joined our lab as a Ph.D. student on June 23
She has also been appointed as a trainee on Northwestern’s NIH-funded Molecular Biophysics Training Program (MBTP, T32). Congratulations, Sarah!
Goodbye and good luck to Richard Massimino
Today is Richard’s last day in the lab. He will be joining St. Jude Children’s Research Hospital as a PhD student. We wish him the best in his future endeavors!